Public hospitals will provide second-tier NIPT and CMA services for high-risk pregnant women. For low-risk mums who are not eligible for either NIPT or CMA in public hospitals but want to know more about condition of their foetus, Dr Leung points out that spending maximum $10,000 is good enough for one to have more information by doing prenatal genetic and genomic tests in private medical organisations. “Take an NIPT as first-tier screening for around $5,000; followed by a foetal anomaly ultrasound examination for $3,000, which is not offered to pregnant women under 35 in public hospitals.” Dr Leung highlights that there are numerous suppliers of NIPT in the market, most of which have more or less similar performance. Doing the test once is sufficient. Moreover, expectant mothers should not miss the ultrasound examination for foetal nuchal translucency, skin thickness at the back of the baby’s neck, be it done in a public hospital or private clinic. High nuchal translucency (≥3.5mm) not only indicates the risk of Down syndrome but also other congenital abnormalities.